Description
Methadone uk
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What is Methadone?
Methadone is a synthetic opioid that is used to relieve pain and treat heroin, fentanyl, and oxycodone addiction. Methadone is similar to morphine but has a gradual onset and milder effects. but has accepted medical uses and can be prescribed. You do not necessarily need a prescription to Buy Dolophine Methadone powder online from Ultra MEDICS.
Is Methadone an Opiate?
Methadone is commonly referred to as an opiate, although it is technically an opioid. Opioids are synthetic versions of naturally occurring opiates, but the terms opiate and opioid are frequently used interchangeably. Opioids and opiates are both narcotics.
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Legal methadone uses are limited to relieving severe pain and as a way to manage withdrawal symptoms associated with heroin (or other narcotic) addiction. Due to its addictive nature, the illicit use of methadone is common.
Pain Management
Opioids manage pain symptoms by binding to opioid receptors located in the central nervous system, thereby blocking pain signaling in the brain. Prescriptions of methadone for pain management have become somewhat controversial in recent years, mainly due to the addictive nature and the risk of selling or giving away prescribed pills or powder.
- Chronic Pain: Chronic pain affects more than 40% of older Americans. Prescriptions of methadone for chronic pain management were common until recently, but mounting evidence suggests that long term opioid use for chronic pain management may cause more problems than solutions. Many people who use methadone to manage chronic pain report that they develop tolerance to the medication, resulting in the requirement for ever-increasing doses in order to continue to manage their pain. Consequently, long-term methadone use for pain management leads to addiction, withdrawal symptoms, and unmanaged pain.
- Cancer Pain: Many people undergoing treatment for various cancers suffer from moderate to severe pain, and methadone has been shown to be a reliable first-line therapy in the management of cancer pain. Interestingly, many lines of tumor cells have been shown to have opioid receptors. In these patients, methadone could have “tumor thermogenic” properties; that is, methadone could control pain as well as enhance the efficacy of anti-tumor agents.
- Back Pain: Chronic lower back pain is one of the most prevalent pain syndromes among adults in the United States, affecting 13.1% of adults ages 20 to 69.
Addiction Treatment: How Does Methadone Work for Addiction?
Opioids are among the most powerfully addictive drugs known to man. Common opioids of abuse include heroin, fentanyl, oxycodone, and morphine. Although methadone is an opioid, it has a more gradual onset of action than other opioids and the overall effect is mild enough that users do not experience the euphoric high that is associated with other opioids of abuse. Buy Dolophine Methadone powder online.
Underlying all opioid addictions are significant changes in brain chemistry, primarily associated with mu-opioid receptors and the dopamine-mediated reward system. Opioid use rapidly induces a state of tolerance, meaning that a person must take ever-increasing doses of the drug to feel the desired effect.
Physical dependence and addiction quickly develop with regular opioid use, and withdrawal symptoms can be profoundly debilitating. When people discontinue opioid use, physical symptoms generally subside within days or weeks, but the chemical changes in the brain may persist for years. Because methadone acts on the same brain regions as other opioids without delivering the euphoric high, methadone can stave off physical and psychological withdrawal symptoms associated with heroin and other opioids. For individuals who struggle with chronic opioid addiction, methadone treatment may be a lifelong strategy that allows them to avoid relapse. However, methadone itself is associated with dependence and addiction. Long-term methadone treatment strategies should be reserved for extreme cases of opioid addiction.
How is Methadone Taken?
Methadone administration is generally oral (pill or liquid). In hospitals or clinics, injections may be used. Illicit methadone use is often associated with smoking or snorting.
- Pill: Methadone pills typically come in 5 mg or 10 mg doses, and may come in wafer or tablet formulations.
- Liquid: Methadone liquid may come as a concentrate (10 mg) or ready-to-use solutions (1 mg or 2 mg). Liquid methadone for oral delivery must be precisely measured. There is also a soluble tablet available.
- Injection: Subcutaneous, intravenous, or intramuscular injections are generally given by health care providers in clinical settings for pain management or acute withdrawal symptoms. Some people use methadone injections illicitly for the fast-acting effect, the results of which can be lethal.
- Smoke inhalation: Smoking methadone is dangerous and is never medically sanctioned. Smoking methadone delivers effects quickly, which is why it is so popular among recreational users.
- Snorting: Snorting methadone is also popular among recreational users. Snorting does not provide the near-immediate onset that injecting or smoking does, but it has a more rapid onset compared to oral administration.
What Does Methadone Look Like?
Methadone generally comes in the form of round, white pills, although some may be beige or orange, depending on the manufacturer and dosage. Methadone can be dissolved in water, so liquid methadone is clear and flavorless, although it may be flavored cherry or citrus and colored red or orange. Buy Dolophine Methadone powder online.
Other Names for Methadone
Methadone hydrochloride is the active component in methadone formulations. The brand name for methadone UltraMEDICS supplies and recreational users created several street names;
- Generic: Methadone hydrochloride
- Brand: Dolophine
- Street: Fizzies, amidone, chocolate chip cookies
Methadone Side Effects
Methadone is associated with a number of common side effects, including restlessness, anxiety, sleepiness, dizziness, nausea, vomiting, itchy skin, pupil contraction, sweating, constipation, and sexual dysfunction. In rare cases, or in cases of overdose, respiratory depression (slowed breathing) or slowed heart rate can occur, which may lead to coma or death.
How Long Does Methadone Stay in Your System?
The length of time that methadone is measurable in your system can be variable depending on the quantity used and route of administration. In addition, different tests have different sensitivities. Buy Dolophine Methadone powder online.
- Blood: Up to two-and-a-half days
- Urine: Up to seven days
- Hair: Up to several months
- Breastmilk: The American Academy of Pediatrics indicates that breastfeeding women can safely use methadone.